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Check out the top Python frameworks that developers and QAs can use for web development and software testing.

Nazneen Ahmad
February 8, 2026
Among various programming languages, Python is becoming the popular programming language in web development and testing due to its versatility, simplicity, and readability.
When we think of Python frameworks, many names come to our minds. This often confuses us regarding which is most appropriate for software projects. However, if we look ahead to the future, what will the popular Python frameworks be in 2025?
To clear this up, I have curated a detailed list of the most popular Python frameworks for software development and testing. You will get information on the features and benefits of these frameworks, which you should keep in mind when looking for Python frameworks.
In Python, the framework is a collection of pre-written codes that gives developers a set of tools and structures to build applications efficiently. In other words, you can understand this as a collection of modules or packages that help developers build web applications. Mainly, the Python framework is a set of tools that lay the foundations for building applications, so you don’t have to start from scratch every time.
Python framework can help developers by providing the following aspects:
A Python framework can be either full stack, asynchronous or micro. However, before digging into the Python framework in detail, I will briefly introduce them in the below section.
Python frameworks are divided into three main categories that define its specification. Here are those three Python frameworks explained.
It comprises all web development requirements and offers all-in-one solutions. This indicates that a full-stack framework provides all features and tools needed to build web applications from start to finish. For example, it includes form generators, form validation, template layouts, and many more. Basically, this provides everything required to develop a web application, like a template engine, ORM, and admin interface.
Some popular Full-Stack Python frameworks include Django, Web2py, CubicWeb, Giotto, FastAPI, Pylons framework, TurboGears, BlueBream, and Websauna.
It is a lightweight framework used for minimalistic web application development because it provides only the bare essentials needed to build them. For example, routing, request and response handling, and HTTP protocol support. Hence, this provides developers with only a minimum set of functionalities, allowing them to build lightweight and fast web applications.
Unlike a Full-Stack framework, it does not provide additional features like database abstraction, form validation, etc. However, it requires more manual work from developers. This includes manually adding other code and requirements or using third-party libraries and tools to implement the desired functionality. If you take this in a different sense, using microframework, you get more flexibility and customization options because of more control over their code.
Some popular Micro Python frameworks include Flask, Dash, Falcon, MorePath, Pycnic, and Hug.
Asynchronous Python frameworks allow developers to write asynchronous code, meaning the code can execute multiple tasks simultaneously without blocking other tasks. It is designed to handle a large set of concurrent connections and processes, which means managing multiple requests simultaneously without blocking the program’s execution. Using this framework, developers write codes that can be run concurrently, enabling faster and more efficient data processing.
It utilizes the asyncio library in Python, which provides a way to write asynchronous code using coroutines and event loops. Some popular Asynchronous Python frameworks include Sanic, AIOHTTP, Growler, and Tornado.
When you develop web applications or mobile apps, there are the majority of redundant operations like handling HTTP requests and responses, routing, database interactions, user authentication and authorization, input validation, and others. You always want a framework that can save time and effort in software application development. This is possible by leveraging pre-built tools and components of Python frameworks.
Python frameworks allow developers to reuse code for different tasks like HTTP operations, etc. Hence, you don’t have to re-write the code from scratch, making the development process quick and efficient.
It is easy to use Python frameworks to build and maintain software applications because it is structured in a way that allows modularity and code organization. Some standard structure features include MVC architecture, middleware, and configuration. This makes it easier for developers to understand and maintain the codebase, even as the application scales.
Below, I have curated an exhaustive list of the best Python frameworks for web development and automation testing so that you get all information in one place.
Python testing frameworks are a crucial part of the web application development process that helps in testing your code to ensure it gives correct functionality.
When it comes to choosing Python frameworks for testing, you have to consider the key information that defines its specificity. For example, you should look for its ability, script quality, simplicity of test cases, and other factors.
Robot Framework is an open-source test automation framework that simplifies writing test cases and makes them more readable and clear based on the keyword-driven approach. The thing that makes it one of the most popular Python frameworks is its specificity for acceptance testing, acceptance test-driven development, behavior-driven development, and robotic process automation.

Further, the use of tabular syntax to write test cases and a large ecosystem of libraries and tools also make it a popular choice for test automation. When you use the Robot Framework, you should also know that although it is based on Python, it works seamlessly with Jython and IronPython (.net based).
This diversifies its ability to test your code. All you need is to install Python version 2.7.14 or higher, install the Python package manager (pip), and download development frameworks like PyCharm Community Edition.
GitHub: 10.3k Star and 2.4k Fork as of March 2025.
Key features of Robot Framework
pytest is one of the most widely used Python frameworks, which is open source and supports unit testing, functional testing, and API testing. It is easy to use and learn, which also extends to be utilized for individual practice groups and open-source projects. This is possible by its simple and intuitive syntax that allows easy writing and running of automation tests.
All you need is to install Python version 3.5 and above.

GitHub: 12.5k Star and 2.8k Fork as of March 2025.
Key features of pytest:
Behave is considered one of the best Python frameworks for testing, which is particularly useful when it comes to Behavior-Driven Development (BDD). It is an Agile development method that helps developers, stakeholders, and quality analysts work together. When you use Behave, it is easy to execute BDD without any hurdles. It is very much similar to Cucumber.
When using Behave, all test scripts are created in simple language and then added to the running code. It enables the reuse of previously defined steps in other use-case scenarios. To start with the Behave framework, you need to install Python 2.7.14, pip and set up PyCharm.
On a side note, you can automate your Selenium BDD test suites on a scalable TestMu AI cloud grid with Behave framework.

GitHub: 3.3k Star and 650 Fork as of March 2025.
Key features of Behave:
Lettuce is another one of the popular Python frameworks for BDD, based on Cucumber. The primary intention of Lettuce is to focus on tasks of Behavior-Driven Development. This makes the process of defining scenarios, automating the test execution, and generating reports on the results simple and easy.

GitHub: 1.3k Star and 322 Fork as of March 2025.
To get started with Lettuce, you need to set up Python 2.7.14 and above, install PyCharm or a similar IDE, and use the package manager for Python.
Key features of Lettuce:
Doctest is a built-in module in the Python programming language’s standard library. Using doctest allows the developers and testers to create tests based on the output of the Python interpreter shell. This indicates that developers can write test cases by giving input values and then enable a robust comparison of actual output with the expected output.
While testing, developers need to cut and paste the test cases in the docstrings of Python code. The doctest module will then automatically extract the test cases and allow its run to verify the output matches the expected result.

GitHub: 6.1k Star and 653 Fork as of March 2025.
Key features of doctest:
Nose2 is the replacement for the nose framework. It extends PyUnit beyond its functionality with its added plugins, which support test execution, test discovery, fixtures, decorators, and parameterization.

GitHub: 800 Star and 131 Fork as of March 2025.
Key features of nose2:
Testify is a Python-based framework mainly used for integration and system testing. It intends to replace the unittest and nose framework and add some advanced features to it. Some of those include better support for mocking, parallel test execution, and more detailed reporting of test results.

GitHub: 306 Star and 66 Fork as of March 2025.
Key features of Testify:
unittest is a Python-based framework modeled after JUnit. This framework is standardized and included by default with the Python package. It allows automated testing that helps you share code for setting up and closing out tests, organizes your tests into groups, and ensures your tests are separate from any reporting system you use. unittest is also known as PyUnit.

GitHub: 2 Star and 1 Fork as of March 2025.
Key features of unittest:
The true capability of using the Python framework can be leveraged by testing your web application on the cloud. It provides on-demand resources that can scale up or down depending on your requirements.
AI-native test execution platforms like TestMu AI lets you perform Python automation testing on an online browser farm of real browsers, devices, and OS. It supports various Python frameworks for Selenium Python testing like pytest, Behave, Robot, unittest, Lettuce, etc., allowing you to perform tests with your preferred Python testing framework.
Visit our documentation to get started with automation testing using Python.
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Python is a popular programming language, in addition to testing, it is also widely used for web development. What makes it the ideal choice? It is the simplicity and flexibility of the Python-based framework. There are several Python frameworks available for web development.
Here is a list of several Python frameworks for web development that will work well for you in 2025.
Django is one of the most popular Python frameworks that is an open-source and high-level full-stack framework. It comprises all the required Python features and components that a developer would need to develop a web application, like database connectivity and user authentication.

What makes Django unique and specific from other frameworks? It is the principle of DRY (Don’t Repeat Yourself) that is followed. It emphasizes the significance of reducing the duplication of codes. This helps in improving maintainability, reducing bugs, and increasing productivity.
GitHub: 82.5k Star, 32.3k Fork as of March 2025.
Key Features of Django:
Web2py is an open-source Python framework that can be run on all popular operating systems. It has a web-based IDE, including a code editor, debugger, and one-click deployment. This makes it an independent framework where development, database administration, testing, debugging, deployment, and maintenance of applications, can all be executed through the web interface.

Web2py follows MVT architecture patterns that allow developers to manage their code and separate the distinct aspects of a web application into diverse layers. This helps to maintain and extend the application over time.
GitHub: 2.1k Star and 906 Fork as of March 2025.
Key features:
Flask is licensed under Berkeley Software Distribution (BSD), which indicates that it is free and open source. It is one of the most popular Python web frameworks classified as a micro-framework that is easy to use and lightweight. The main reason for the above is that it does not have particular libraries and tools for web application development.

Flask has no form validation or database abstraction layers, mainly in large web frameworks. However, the common functions are provided by third-party extensions, which enable adding features to the application.
GitHub: 68.9k Star and 16.3 Fork as of March 2025.
Key features of Flask:
Bottle is a lightweight and simple WSGI micro web framework for prototyping and building simple personal applications. It is distributed as a single file module and creates a single source file for different applications developed using the Bottle framework. There are no dependencies for developing web applications other than Python’s standard library.

The amazing functionality of Bottle includes utilities directing, templating and fundamental abstraction. This enables developers to work closely with hardware to build personalized use apps.
GitHub: 8.5k Star and 1.5k Fork as of March 2025.
Key features of Bottle:
CherryPy is a Pythonic and object-oriented framework that helps developers build web applications similar to other object-oriented Python programs. This allows smaller source code to be developed in less time. It was released in 2002 and marked to be one of the oldest Python frameworks to be used widely by developers.

You do not need to install Apache to run CherryPy. The application developed using CherryPy is embedded with its multi-threaded web servers and executed on any OS. Further, the best part of CherryPy is that you can use any type of technology for developing templates and data access.
GitHub: 1.9k Star and 368 Fork as of March 2025.
Key features of CherryPy:
Pyramid framework is an open-source and small Python web framework developed as part of the Pylons projects. It is licensed under a BSD-like license, which indicates that it can be used in proprietary and open-source projects.

It allows Python developers to create web applications easily with minimalistic complexity. It is structured to build real-world web applications with quick deployment. Further, the most preferred aspect of Pyramid is its ability to work equally with small and full-scale applications.
GitHub: 4k Star and 887 Fork as of March 2025.
Key features of Pyramid:
Dash is an open-source Python framework designed mainly to build visual data interfaces. It was launched in 2017 as a Python library and later developed and grown to have R, Julia, and F#. With its ability to abstract complexities of web development, like working with multiple programming languages (CSS, JavaScript), it has simplified the process of building web applications.

Now, it has become one of the favorite frameworks of data scientists, as they can build analytical web applications without requiring any advanced web development knowledge like JavaScript. They can develop their web application entirely on Python by just using simple syntax to define its layouts and behavior.
The core of Dash constitutes three major technologies:
GitHub: 22k Star and 2.1k Fork as of March 2025.
Key features of Dash:
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AIOHTTP is a Python framework built on top of Python’s asyncio library, which allows asynchronous programming in Python. For example, it allows the use of async/await syntax and handles multiple requests simultaneously by not blocking the execution of the program. AIOHTTP can be used to create web applications and APIs for clients and servers.

It is a server web framework and is also used as a client framework to handle HTTP requests to other servers. Further, it also provides a simple API to make HTTP requests to other servers.
GitHub: 15.5k Star and 2.1k Fork as of March 2025.
Key features of AIOHTTP:
CubicWeb framework was developed by Logilab. It is a freely available, semantic, and Python-based framework based on data models. When we compare this other Python framework that uses separate views and models, CubicWeb is quite different as it uses cubes which are independent components.
These are reusable modules with a specific set of functionality where each cube comprises the data model, views, controller, and others that determine the application’s functionality.

Here, the cubes are integrated to develop web applications based on CubicWeb, which can also be connected to a database, web servers, and others. Such cubes can also be shared, extended, and modified, thus allowing easy-to-reuse code, creating the flexible architecture of web applications, and lowering their development time.
GitHub: 1 Star and 2 Fork as of March 2025.
Key features of CubicWeb:
Falcon is a minimalistic ASGI (Asynchronous Server Gateway Interface)/WSGI (Web Server Gateway Interface) framework for Python focused on building REST APIs and microservices. It emphasizes the reliability, performance, and correctness of the Falcon web application developed.
Thus, if you want to develop critical applications that require a high level of functionality and quality, Falcon can be a good choice. Popular applications like LinkedIn, OpenStack, and RackSpace use Falcon.

GitHub: 9.6k Star and 953 Fork as of March 2025.
Key features of Falcon:
Giotto is a Python web framework that supports functional styles where the decoupling of model, view, and controller code is done. This shows that web designers, developers, and system administrators can work independently. Here, the model layer manages data and business logic. The view layer presents data to a user in a visually appealing way. The controller layer is an intermediary layer between the model and the view layer, which handles user input.

It also has controller modules that help users to create web applications on different platforms like the web, IRC, and command line.
GitHub: 60 Star and 10 Fork as of March 2025.
Key features of Giotto:
Growler is a Python framework based, built on top of asyncio, an asynchronous library as marked in PEP 3156. It is added to the standard library in Python 3.4. It is inspired by Node.js and Express/Connect, popular frameworks in the JavaScript programming language.

GitHub: 686 Star and 29 Fork as of March 2025.
Key features of Growler:
Hug is a Python framework that intends to develop a simple Python-driven API. It is one of the most preferred choices of developers to create RESTful API quickly with less boilerplate code. The main reason is its simplicity and ease of use. It has clean and simple syntax for defining API endpoints, which allows for building application logic.

Further, Hug is well known for its performance and claims to be the fastest web framework for Python 3. This is because Hug only uses system resources like CPU and memory usage when required. It uses Cython to compile Python code into C code and then into machine code which is executed faster than Python code.
GitHub: 6.9k Star and 387 Fork as of March 2025.
Key features of Hug:
FastAPI is a high-performing web framework for building APIs using Python 3.7 or higher. FastAPI is based on standard Python-type hints, which can be understood as annotations that help developers specify the type of function argument and return values. This makes writing and maintaining code very easy because you can use type hints to detect the error at the earliest. This often leads to improving code readability and documentation.

GitHub: 81.5k Star and 7k Fork as of March 2025.
Key features of FastAPI:
Morepath is a microframework designed to create web applications with fewer setup requirements. Morepath is based on Web Server Gateway Interface (WSGI), a standard Python interface for interaction between web servers and web applications. It is mainly designed to get typical use cases for fast execution in developing web applications and the creation of RESTful Web Services with the use of Python data structure.

GitHub: 393 Star and 34 Fork as of March 2025.
Key features of Morepath:
Pycnic is a Python-based microframework designed to build fast and efficient JSON-based APIs. Pycnic works according to the principle of object-oriented programming and is optimized to handle JSON data. It is a small and standalone framework with less footprint, making it fast and efficient. If you’re interested in diving deeper into object-oriented programming concepts, exploring oops interview questions interview questions can be an excellent way to solidify your understanding and prepare for technical interviews.

GitHub: 158 Star and 26 Fork as of March 2025.
Key feature of Pycnic:
Pylons is an open-source Python-based full-stack framework intended to develop web applications quickly. It provides developers with a complete set of tools and features needed to develop frontend and backend components of web applications. It also incorporates properties of languages like Perl, Ruby, and Python, making it a powerful tool for developers.

Pylons framework allows web application development concisely, ranging from as small as single Python modules to large-scale projects with complex directory structures. It has project templates using which developers can boot-strap the new application projects. It even gives the option to start from scratch in developing web applications that include the basic directory structure and files needed to get started with the project.
GitHub: 233 Star and 76 Fork as of March 2025.
Key features of Pylons:
Sanic is an open-source Python framework built on top of Python’s uvloop library, allowing it to handle high levels of concurrency with minimal overhead. It is specifically designed to provide HTTP response by asynchronous request handling. This makes it compatible with Python 3.5’s async/await functions, enhances speed, and improves the non-blocking ability of the framework.

It is proven to perform well even under heavy loads. In the benchmark test, Sanic was able to handle 33,000+ requests in a second. Such speed makes it the most appropriate choice for applications that require high-performance web servers like real-time data processing, high-traffic web applications, and streaming.
GitHub: 18.3k Star and 1.6 Fork as of March 2025.
Key features of Sanic:
Tornado is one of the popular Python frameworks designed to handle and manage high levels of traffic and able to maintain long-lived connections to users. In other words, it is an excellent choice for a web application with real-time updates and a long polling connection.

Tornado is an asynchronous networking library with tools and abstractions allowing developers to build scalable, high-performance networked applications. For example, these tools include support for non-blocking I/O, network sockets, and other low-level networking operations.
GitHub: 21.9k Star and 5.5k Fork as of March 2025.
Key features of Tornado:
TurboGears is a full-stack web application framework that allows the easing of the development of data-driven web applications. It provides all the required components for the development of web applications like database connectivity, front-end technologies like React, Vue.js, and Angular, back-end development tools, and templating.

TurboGears helps web developers to integrate JavaScripts development tools with their Python-based web applications. This enables the developers to use such tools to build single-page and traditional multi-page applications.
GitHub: 810 Star and 80 Fork as of March 2025.
Key features of TurboGears:
Grok is an open-source web development framework that gives agile development experience to all developers using Python by leveraging Zope Toolkit (ZTK) technology. It focuses on two general principles, which include DRY (Don’t Repeat Yourself) and convention over configuration.

Here, the principle of convention over configuration indicates that Grok has default conventions and assumptions regarding the structuring and configuration of web applications. Such approaches help developers to write code quickly for any specific application logic. Further, based on the DRY principle, Grok enables developers to remove any redundancy by not duplicating the code and configurations.
GitHub: 28 Star and 15 Fork as of March 2025.
Key features of Grok:
BlueBream is an open-source Python framework designed to build online complex and large-size web applications. It is a server and library too. Earlier, it was called Zope 3 and developed by the Zope team.
The framework was built on top of the Web Server Gateway Interface specification, through which it is easy to interact with Python web applications and web servers. With this, BlueBream can be deployed on a wide range of web servers and platforms.

Key features of BlueBream:
Quixote is the Python framework for developing web applications to improve performance and offer flexibility. Quixote uses traditional technologies, including server-side programming language, rather than new technologies like Single Page Applications (SPAs).

With Python classes and functions, the logic for formatting web pages is easily defined. It does not cause any enforcement to separate the presentation of logic and back-end logic. Instead, it uses traditional techniques for the structuring of code. One approach could be to segregate presentation logic into its individual sub-packages. This allows cleaner and maintainable code.
GitHub: 88 Star and 13 Fork as of March 2025.
Key features of Quixote:
Weppy is the lightweight and high-performance WSGI web framework used for developing high-quality web applications.

GitHub: 1 Star and 0 Fork as of March 2025.
Key features of Weppy:
Masonite is a Python web framework that follows Model-View-Controller (MVC) architectural pattern. This gives developers easy-to-use syntax to develop web applications.

GitHub: 2.2k Star and 127 Fork as of March 2025.
Key features of Masonite:
Jam.py is a Python web framework that helps developers to create web applications using the DRY principle. It focuses on CRUD (Create, Read, Update, and Delete) operations.

GitHub: 455 Star and 88 Fork as of March 2025.
Key features of Jam.py:
Reahl is a web framework that helps developers build web applications using Python. It can also be used to customize and compose widgets in usual Python code.

GitHub: 130 Star and 7 Fork as of March 2025.
Key feature of Reahl:
Websauna is the Python framework for developing websites and backends for customers and businesses. Websauna was created with modern Python 3 features, SQLAlchemy, and Pyramid web routing framework.

GitHub: 262 Star and 55 Fork as of March 2025.
Key features of Websauna:
Wheezy.web is a lightweight and high-performance WSGI web framework in Python. It gives simple and useful tools for developing web applications.

GitHub: 26 Star and 0 fork as of March 2025.
Key features of wheezy.web:
Zope is a web application server and framework based on Python. Zope was released in 1998 and progressed into many different applications, frameworks, tools, and libraries.

GitHub: 361 Star and 101 Fork as of March 2025.
Key features of Zope:
Quart is a lightweight and async Python web microframework. Quart is designed to be compatible with the Flask web framework that uses the asyncio library to give an asynchronous programming model.

GitHub: 3.2k Star and 170 Fork as of March 2025.
Key features of Quart:
Once you have developed web or mobile applications using your preferred Python framework, you can test them on a digital experience testing cloud like TestMu AI to ensure your Python website or mobile app gives a uniform experience across all browsers, devices, and operating systems combinations.
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Development of web applications based on Python gives you various options in terms of the frameworks using which you can structure high-quality applications. However, deciding the right framework that aligns with the web project’s needs may be challenging. This is because of the availability of several Python frameworks for web development and testing with similar features.
Choosing the right Python framework requires considering factors that help you make better decisions. First, you need to be familiar with the requirements of web development projects. For example, you may ask
If you understand the right requirement, it is easy to narrow down the list of possible Python frameworks, and among those, you can select the most appropriate one.
Another factor you should consider is around community and support offered by the Python framework. For example, is the framework widely used and well-established? Is there an active community of developers contributing to the framework and providing support? Answering such questions will give you an idea of a well-supported framework that ensures you access resources while developing and testing web applications.
You should address the Python framework’s learning curve and ease of use. Always be inclined to select a Python framework that is easy to learn and helps you get started with the testing and development process.
However, no single factor should be considered when choosing the right Python framework. Therefore, the appropriate framework will entirely depend on associated factors and the specific needs and requirements of your web development and testing projects.
Python will progress to remain popular among developers and testers for the release of quality web applications in 2025. The demand for web and mobile applications increases with new software technologies and methodologies. Therefore, the requirement for an efficient Python framework will increase more than ever in the coming year.
In this blog, I have discussed 39 Python frameworks likely to dominate the software development and testing landscape in 2025. Their required and unique features and capabilities allow easy testing of software applications, ensuring reliability and scalability.
I hope this blog will help to get good information on different Python frameworks for your software project needs.
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